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Core functions

vizAPOTC() stable
Directly visualize clonal expansion of a combined seurat object
RunAPOTC() stable
Run the APackOfTheClones method on a combined Seurat object for downstream visualization of clonal expansion
APOTCPlot() stable
Various variations of visualizations of clonal expansion post-RunAPOTC
AdjustAPOTC() stable
Adjust the parameters of the APackOfTheClones reduction in a seurat object

Working with RunAPOTC runs

getApotcDataIds() stable
Get all run ids of previous RunAPOTC runs on a seurat object
getLastApotcDataId() stable
Get the object id of the most recent RunAPOTC run on a seurat object
containsApotcRun() stable
Check for the existence of an APackOfTheClones run with its run id
renameApotcRun() stable
Rename an APackOfTheClones run
deleteApotcData() stable
Delete the results of an APackOfTheClones run

Further Customization of Clonal Expansion Plots

showCloneHighlight() experimental
Highlight specific clones on an APackOfTheClones ggplot
overlayLegend() stable
overlay a clone size legend on an APackOfTheClones plot
removeLegend() stable
Remove current APackOfTheClones legend

Clonal Analysis Utilities

countCloneSizes() stable
count the number of clonotype sizes in a seurat object combined with a VDJ library overall or by cluster
mergeCloneSizes()
Merge a list of Clustered Clonotype Frequency Tables
getSharedClones() stable
Compute a list of clonotypes that are shared between seurat clusters
getReductionCentroids() stable
Calculate seurat cluster centroids based on a Dimensional reduction

Data

combined_pbmc stable
Example Multi-sampled T-cell seurat object with integrated TCR library